CONNIE J. MULLIGAN

               

Address:                     Department of Anthropology

409 Genetics Institute, Cancer/Genetics Research Complex

                                    1376 Mowry Rd, PO Box 103610

                                    University of Florida

                                    Gainesville, FL 32610-3610

Telephone:                 (352) 273-8092 (office), (352) 273-8091 (lab), (352) 273-8284 (fax)

E-mail:                        cmulligan@ufl.edu

 

POSITIONS HELD

2007-2008          Colonel Allan R. and Margaret G. Crow Term Professor

2008 - present     Affiliate Associate Professor, Center for African Studies, University of Florida

2005 - present     Associate Professor, Department of Anthropology, University of Florida

2003 - present     Associate Director, University of Florida Genetics Institute

1999 - 2005        Assistant Professor, Department of Anthropology, University of Florida

1998 - 2000        National Research Council Senior Research Associate, NIAAA, NIH

1995 - 1998        Research Biologist, Smithsonian Center for Materials Research and Education

1991 - 1995        Postdoctoral Fellow, Smithsonian Tropical Research Institute, Republic of Panamá

1990 - 1991        Postdoctoral Fellow, Molecular Biophysics and Biochemistry, Yale University

 

EDUCATION

1990         Ph.D., Molecular Biophysics and Biochemistry, Prof. Dieter Söll, Yale University

1985                 M.Phil., Molecular Biophysics and Biochemistry, Yale University

1983         B.S., Honors Biology and Chemistry, University of Illinois, Champaign-Urbana

 

GRANTS

2008                NSF Grant (BCS-0820687), “Genetics ancestry, race and health disparities: A biocultural approach”, $391,586, 7/15/08-7/14/11 (PI)

2005                NSF Grant BCS-0518530, “Human dispersals out of Africa: Mitochondrial and Y chromosomal genetic analysis of Eritrean and Omani populations”, $311,708 + Supplement - $2,813 (2006) + REU supplement - $8,000 (2007), 7/29/05-7/28/08, (PI)

2005                NSF Grant, “Domestication of the donkey: Aridity, mobility, and the development of the African pastoral societies”, PI-Dr. Fiona Marshall, Washington University, St. Louis, MO, $32,000 (2005/2006) + $5,600 (2006) + $7,500 (2007), 1/1/05-12/31/07 (contract)

2002                NSF Grant BCS-0129721, "Acquisition of an automated DNA analysis system", $42,000 with matching funds from the College of Liberal Arts and Sciences, 2/1/02 (PI)

2001                NIH Grant R03 AA12906, "Genotype:phenotype associations in alcoholism and alcohol-related disorders", $144,500, 5/11/01-5/31/03 (PI)

2001                NIH Training Grant AA07561-09, "Training in alcohol and neurodegenerative disease", $191,391, 7/1/93-6/30/03 (1 of 15 preceptors)

 

PUBLICATIONS (I have published as Mulligan, Kolman, and Kline)

Kitchen A, Ehret D, Assefa S, Mulligan CJ. 2009. Bayesian phylogenetic analysis of Semitic languages identifies an Early Bronze Age origin of Semitic in the Near East, Proc R Soc B [epub ahead of print] doi: 10.1098/rspb.2009.0408.

Cerný V, Fernandes V, Costa MD, Hajek M, Mulligan CJ, Pereira L. 2009. Migration of Chadic speaking pastoralists within Africa based on population structure of Chad Basin and phylogeography of mitochondrial L3f haplogroup, BMC Evol Biol , 9(1):63 [epub ahead of print] doi:10.1186/1471-2148-9-63.

Mulligan CJ, Kitchen A, Miyamoto MM. 2008. Updated three-stage model for the peopling of the Americas, PLoS ONE, 3(9):e3199.

Cerný V, Pereira L, Kujanová M, Hájek M, Vašíková A, Morris M, Mulligan CJ. 2009. Out of Arabia – the settlement of island Soqotra as revealed by mitochondrial and Y chromosome genetic diversity, Am J Phys Anthropol, 138:439-447.

Ascunce MS, González-Oliver A, Mulligan CJ. 2008. Y chromosome variability in four Native American populations from Panamá, Hum Biol, 80:287-302.

Cerný V, Mulligan CJ, Rídl J, Zaloudková M, Edens CM, Hájek M, Pereira L. 2008. Regional differences in the distribution of the sub-Saharan, West Eurasian, and South Asian mtDNA lineages in Yemen, Am J Phys Anthropol, 136:128-137.

Kitchen D, Miyamoto MM, Mulligan CJ. 2008. A three-stage colonization model for the peopling of the Americas, PLoS ONE, 2(9):e829.

Kitchen A, Miyamoto MM, Mulligan CJ. 2008. Utility of DNA viruses for studying human host history: Case study of JC virus, Mol Phylogenet Evol, 46:673-682.

Mulligan CJ, Norris SJ, Lukehart SA. 2008. Molecular studies in Treponema pallidum evolution: Toward clarity? PLoS Neg Trop Dis, online Jan 15.

Tamm E, Kivisild T, Reidla M, Metspalu M, Smith DG, Mulligan CJ, et al. 2007. Beringian Standstill and Spread of Native American Founders, PLoS One, Sept 5:2(9):e829.

Bhaskar LVKS, Thangaraj K, Mulligan CJ, Papa Rao A, Shah AM, Sabeera B, Reddy AG, Singh L, Rao VR. 2008. Allelic variation and haplotype structure of the dopamine receptor gene DRD2 in 9 Indian populations, Genet Testing, 12: 153-160.

Non AL, Kitchen A, Mulligan CJ. 2007. Identification of the most informative regions of the mitochondrial genome for phylogenetic and coalescent analyses, Mol Phylogenet Evol, 44:1164-1171.

Bhaskar LVKS, Thangaraj K, Shah AM, Pardhasaradhi G, Kumar KP, Reddy AG, Rao AP, Mulligan CJ, Singh L and Rao VR. 2007. Allelic variation at the NPY gene in 14 Indian populations, J Hum Genet, 52: 592-598.

Clarimon J, Gray RR, Williams LN, Enoch MA, Robin RW, Albaugh B, Singleton A, Goldman D, Mulligan CJ. 2007. Linkage disequilibrium and association analysis of alpha synuclein (SNCA) and alcohol and drug dependence in two American Indian populations, Alcohol: Clin Exp Res, 31:546-554.

Ascunce MS, Hasson E, Zunino G, Mulligan CJ, Mudry MD. 2007. Mitochondrial sequence diversity of the southernmost extant New World monkey, A caraya, Mol Phylogenet Evol, 43:202-215.

Ascunce MS, Kitchen A, Schmidt PR, Miyamoto MM, Mulligan CJ. 2007. Unusual pattern of ancient DNA mitochondrial DNA haplogroups in northern African cattle, Zoo Studies, 46:123-125.

Mulligan CJ, Kitchen A, Miyamoto MM. 2006. Comment on “Population size does not influence mitochondrial genetic diversity in animals”, Science, 314:1390.

Gray RR, Mulligan CJ, Molini BJ, Sun ES, Giacani L, Godornes C, Kitchen A, Lukehart SA, Centurion-Lara A. 2006. Molecular evolution of the tprC, D, I, K, G, and J genes in the pathogenic genus Treponema, Mol Biol Evol, 23(11): 2220-2233.

Tarskaia L, Gray RR, Burkley B, Mulligan CJ. 2006. Genetic variation at the mitochondrial DNA 9-bp repeat locus in the Sakha of Siberia, Hum Biol, 78:179-198.

Mulligan CJ. 2006. Anthropological applications of ancient DNA: Problems and prospects, Am Antiq, 71:365-380.

Mulligan CJ. 2005. Isolation and analysis of DNA from archaeological, clinical, and natural history specimens, in: Methods in Enzymology, Molecular Evolution: Producing the Biochemical Data, Part B (Zimmer EA and Roalson E, eds), 395:87-103.

Mulligan CJ, Hunley K, Cone S, Long JC. 2004. Population genetics, history, and health patterns in Native Americans, Annual Rev Genomics Hum Genet, 5(1): 295-315.

Mulligan CJ, Robin RW, Osier MV, Sambuughin N, Goldfarb LG, Kittles RA, Diane Hesselbrock, Goldman D, Long JC. 2003. Allelic variation at alcohol metabolism genes (ADH1B, ADH1C, ALDH2) and alcohol dependence in an American Indian population, Hum Genet, 113:325-336.

Sun, G, McGarvey ST, Bayoumi R, Mulligan CJ, Barrantes R, Raskin S, Zhong Y, Akey J, Chakraborty R, Deka R. 2003. Global genetic variation at nine short tandem repeat loci and implications on forensic genetics, Euro J Hum Genet, 11:39-49.

Kolman CJ, Tuross N. 2000. Ancient DNA analysis of human populations, Am J Phys Anthropol, 111: 5-23.

Kolman CJ, Centurion-Lara A, Lukehart SA, Owsley D, Tuross N. 2000. Identification of Treponema pallidum subsp. pallidum in a 200-year-old skeletal specimen, J Infect Dis, 180: 2060-2063.

Kolman CJ. 1999. Molecular anthropology: Progress and perspectives on ancient DNA technology, in: Genomic Diversity: Applications in Human Population Genetics, eds. Papiha SS and Deka R., Plenum Publishing, New York, pp. 183-200.

Batista O, Kolman CJ, Arias TD, Guionneau-Sinclair F, Quiroz E, Bermingham E. 1998. Variación en el ADNmt de dos tribus amerindias chibchas, los ngöbé y cuna de Panamá, Memorias del I Congreso Científico sobre Pueblos Indígenas de Costa Rica y sus Fronteras, Universidad Estatal a Distancia, San José, Costa Rica, pp.15-35.

Iwanaga KK, Eberle M, Kolman CJ, Bermingham E, Watkins DI. 1997. Further diversification of the HLA-B locus in Central American Amerindians: New B*39 and B*51 alleles in the Kuna of Panamá, Tissue Antigens, 50: 251-257.

Kolman CJ, Bermingham E. 1997. Mitochondrial and nuclear DNA diversity in the Chocó and Chibcha Amerinds of Panamá, Genetics, 147: 1289-1302.

Kolman CJ, Sambuughin N, Bermingham E. 1996. Mitochondrial DNA analysis of Mongolian populations and implications for the origin of New World founders, Genetics, 142: 1321-1334.

Batista O, Kolman CJ, Bermingham E. 1995. Mitochondrial DNA diversity in the Kuna Amerinds of Panamá, Hum Mol Genet, 4: 921-929.

Kolman CJ, Bermingham E, Cooke R, Ward RH, Arias T, Guionneau-Sinclair F. 1995. Reduced mtDNA diversity in the Ngöbé Amerinds of Panamá, Genetics, 140:275-283.

Kolman C, Söll D. 1993. SPL1-1, a Saccharomyces cerevisiae mutant affecting tRNA splicing, J Bacteriol, 175: 1433-1442.

Kolman CJ, Toth J, Gonda D. 1992. Identification of a portable determinant of cell cycle function within the carboxyl-terminal domain of the yeast CDC34 (UBC3) ubiquitin conjugating (E2) enzyme, EMBO, 11: 3081-3090.

Kolman JL, Kolman CJ, Miller G. 1992. Marked variation in the size of genomic plasmids among members of a family of related Epstein-Barr viruses, Proc Nat Acad Sci USA, 89: 7772-7776.

Kolman CJ, Snyder M, Söll D. 1988. Genomic organization of tRNA and aminoacyl-tRNA synthetase genes for two amino acids in Saccharomyces cerevisiae, Genomics, 3: 201-206.

Ollis D, Kline CJ, Steitz TA. 1985. Domain of Escherichia coli DNA polymerase showing sequence homology to T7 DNA polymerase, Nature, 313: 818-819.

 

REPORTS

-         Tuross N and Kolman CJ. 2000. Potential for DNA testing of the human remains from Columbia Park, Kennewick, Washington, Report to the Departments of Justice and Interior, http://www.cr.nps.gov/aad/kennewick/tuross_kolman.htm.

 

PROFESSIONAL ACTIVITIES

Service to the department (past three years only)

            1)   Personnel committee, 2007-2009        

            2)   Search committee for Medical Anthropology hire, 2007/2008

            2)   Search committee for Department chair hire, 2005/2006

            3)   Student Financial Award Committee, 2005/2006

            4)   Advisory Committee, 2002 – 2006

 

Service to the college and university

1)      Associate Director, UF Genetics Institute, 2003-present

2)      UF Genetics Institute Executive Committee, 2001-present

3)      Chair, CLAS Genetics Institute Committee, 2001-present

4)      Co-chair, Organizing committee, Florida Genetics conference, 2009

5)      Member, Organizing committee, Florida Genetics conference, 2005, 2007, 2008

6)      Mentor for UF Women’s Leadership Council Mentoring Program, a mentoring program for undergraduate women, 2006

7)      UF review panel for NSF PIRE pre-proposals, 2006

8)      Member, Organizing committee, Florida Bioinformatics Workshop 2005

9)      Member, Organizing committee, UFGI/College of Engineering Bioinformatics Workshop,2004.

 

Service to the profession

1)      Associate Editor for Molecular Biology and Evolution, 2006 – present

2)      NSF Physical Anthropology Senior Grants Panel, 2005 - 2008

3)      NSF Physical Anthropology Doctoral Dissertation Improvement Grant Panel, 2004-2005

4)      Co-organized symposia at annual meeting of American Association for Physical Anthropologists, 1999 and 2005

5)      Reviewed nominees for MacArthur fellowships, Feb 2001, April 2004, March 2008

6)      Ad hoc reviewer for Addiction Biology, African Archaeological Review, AIDS, American Journal of Human Biology, American Journal of Physical Anthropology, Annals of Human Genetics, Archives of General Psychiatry, Human Biology, Journal of Archaeological Science Journal of Molecular Evolution, Molecular Biology and Evolution, Molecular Phylogenetics and Evolution, Molecular Psychiatry, Proceedings: Biological Science, Soc Amer Arch

7)      Ad hoc reviewer for NIH, NSF and US Department of Justice

8)      Special expert, United States Department of Justice and United States Department of Interior, Court case on human remains from Kennewick, Washington. Submitted a written report on the probability that DNA testing would be able to resolve the issue of identification of the Kennewick remains. Feb 3, 2000.

 

Public outreach

1)      Opening speaker for “Year of Darwin” Celebration, Florida Community College, Feb 18, 2008

2)      Invited speaker for Minority Access to Research Careers (MARC) seminar series at University of Virgin Islands, Sept 12, 2007

3)      Featured speaker, "Our Ancient World", Global Educational Workshops for K-12 Teachers, UF International Center, Outreach for the Transnational and Global Studies Center

4)      Featured speaker, UF Institute for Learning in Retirement, Genome and the Concept of Race, Jan 11, 2006

5)      Featured speaker, Genetics and Race, A Question of Race Mini Conference, Anti-Racism Coalition and WUFT-TV, Gainesville, FL, Nov 11, 2003

6)      Featured interviewee, NPR radio show, The Glenn Mitchell show, KERA, Dallas, TX, Dec 2, 1999.